Schwannomatosis in pelvic region topography with neuro-muscular complications: A case report

Introduction: Schwannomatosis is a rare type of neurofibromatosis, usually affects people between ages 25 and 30 years old. causes tumors to develop on the cranial, spinal, peripheral nerves. The most common symptoms are: chronic pain, which can occur anywhere in body be disabling, numbness or weakness various parts body, muscle paresis. Two genes are known cause schwannomatosis. Mutations SMARCB1 LZTR1, suppress tumors, associated with this neurofibromatosis. We report case patient victimized by schwannomas pelvic region and, as consequence, neuromuscular injuries. Case Report: Patient under investigation lesions lumbosacral plexus clinical picture marked pain iliopsoas left ipsilateral involvement obturator nerve (mild paresis adduction thigh allodynia anterolateral region). A positron emission tomography-computed tomography (PET-CT) study was carried out assess nodular findings. Elongated were observed, attenuation soft tissues, located laterally muscle. In biopsy one nodules, result compatible schwannomas. Immunohistochemical assay confirmed positive for Sox10. Conclusion: patient, case, will surgically approached due topography lesion, currently refractory impaired mobility.